Phase II Study of Alisertib as a Single Agent in Recurrent and Refractory Central Nervous System Atypical Teratoid Rhabdoid Tumors (ATRT) and Extra-CNS Malignant Rhabdoid Tumors (MRT) and in Combination Therapy in Newly Diagnosed ATRT

Trial Profile

Phase II Study of Alisertib as a Single Agent in Recurrent and Refractory Central Nervous System Atypical Teratoid Rhabdoid Tumors (ATRT) and Extra-CNS Malignant Rhabdoid Tumors (MRT) and in Combination Therapy in Newly Diagnosed ATRT

Recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Jul 2017

At a glance

  • Drugs Alisertib (Primary) ; Carboplatin; Cisplatin; Cyclophosphamide; Etoposide; Methotrexate; Topotecan; Vincristine
  • Indications Rhabdoid tumour; Teratoma
  • Focus Pharmacodynamics; Pharmacokinetics; Therapeutic Use
  • Most Recent Events

    • 23 Feb 2015 Planned number of patients changed from 160 to 180 as reported by ClinicalTrials.gov record.
    • 10 Jul 2014 New trial record
    • 01 May 2014 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.
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