A Phase 1/2 Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib

Trial Profile

A Phase 1/2 Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib

Completed
Phase of Trial: Phase I/II

Latest Information Update: 25 Oct 2017

At a glance

  • Drugs Ruxolitinib (Primary) ; Erlotinib
  • Indications Adenocarcinoma; Lung cancer; Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 17 Oct 2017 Status changed from active, no longer recruiting to completed.
    • 17 Apr 2017 Planned primary completion date changed from 1 Jun 2017 to 1 Jun 2018.
    • 06 Sep 2016 Toxicity and efficacy results (n=22) published in the Journal of Thoracic Oncology.
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