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A First-in-Human Study for the Evaluation of the Safety, Pharmacokinetics and Antitumor Activity of SAR408701 in Patients With Advanced Solid Tumors

Trial Profile

A First-in-Human Study for the Evaluation of the Safety, Pharmacokinetics and Antitumor Activity of SAR408701 in Patients With Advanced Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Feb 2024

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At a glance

  • Drugs Tusamitamab ravtansine (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Bladder cancer; Cervical cancer; Cholangiocarcinoma; Colorectal cancer; Endometrial cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Small cell lung cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Sanofi
  • Most Recent Events

    • 07 Feb 2024 Planned End Date changed from 29 Feb 2024 to 30 Aug 2024.
    • 21 Nov 2023 Planned End Date changed from 31 Aug 2023 to 29 Feb 2024.
    • 06 Jun 2023 Results (n=186) assessing pooled corneal safety results in patients who received tusa rav 100 mg/m2 Q2W, including cohorts of patients with NSQ NSCLC, colorectal, gastric, or small cell lung cancers presented at the 59th Annual Meeting of the American Society of Clinical Oncology
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