Trial Profile
Syntethic vs. natural estrogen in combined oral contraception- effect on insulin sensitivity, inflammation, coagulation and endometrium. A comparison with a progestin-only preparation
Status:
Completed
Phase of Trial:
Phase IV
Latest Information Update: 26 Jun 2023
Price :
$35
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At a glance
- Drugs Estradiol valerate/dienogest (Primary) ; Dienogest; Ethinylestradiol/dienogest
- Indications Metrorrhagia; Pregnancy
- Focus Pharmacodynamics
- Acronyms SYLVI
- 05 Jan 2023 Results assessing whether Ethinylestradiol in combined hormonal contraceptive has a broader effect on serum proteome compared with estradiol valerate, published in the Human Reproduction
- 01 Oct 2022 Results analyzing secondary outcomes comparing combined oral contraceptives containing EV + dienogest (DNG), EE + DNG, and DNG alone on selected coagulation biomarkers, published in the Acta Obstetricia et Gynecologica Scandinavica
- 06 Sep 2022 Results assessing effects of ethinylestradiol and estradiol valerate on other adrenal steroid hormones published in the Contraception