An open-label, randomized, three-treatment, three-period, crossover study to investigate mutual drug-drug interactions between ACT-064992 and sildenafil in healthy male subjects.

Trial Profile

An open-label, randomized, three-treatment, three-period, crossover study to investigate mutual drug-drug interactions between ACT-064992 and sildenafil in healthy male subjects.

Completed
Phase of Trial: Phase I

Latest Information Update: 14 Aug 2014

At a glance

  • Drugs Macitentan (Primary) ; Sildenafil
  • Indications Eisenmenger complex; Erectile dysfunction; Female infertility; Glioblastoma; Idiopathic pulmonary fibrosis; Pulmonary arterial hypertension; Raynaud's disease; Skin ulcer
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Actelion Pharmaceuticals
  • Most Recent Events

    • 14 Aug 2014 New trial record
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