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An Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Co-administered With Ribavirin (RBV) in Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (Turquoise-IV)

Trial Profile

An Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Co-administered With Ribavirin (RBV) in Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (Turquoise-IV)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 14 Dec 2018

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At a glance

  • Drugs Dasabuvir (Primary) ; Ombitasvir/paritaprevir/ritonavir (Primary) ; Ribavirin
  • Indications Hepatitis C
  • Focus Registrational; Therapeutic Use
  • Acronyms Turquoise-IV
  • Sponsors AbbVie
  • Most Recent Events

    • 23 May 2016 Time frame of the primary end point is changed from 12 weeks after the last dose of study drug to Post-treatment Day 1 to Post-treatment Week 12.
    • 20 Jan 2016 Status changed from active, no longer recruiting to completed, as reported by ClinicalTrials.gov.
    • 03 May 2015 Planned primary completion date changed from 1 Nov 2015 to 1 Dec 2015 as per ClinicalTrials.gov record.
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