A Phase 1/2, Open-Label Study to Assess the Safety and Tolerability of Repeat Doses of Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects Following Cyclophosphamide Conditioning

Trial Profile

A Phase 1/2, Open-Label Study to Assess the Safety and Tolerability of Repeat Doses of Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects Following Cyclophosphamide Conditioning

Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Jan 2017

At a glance

  • Drugs SB 728 T (Primary) ; Cyclophosphamide
  • Indications HIV infections
  • Focus Adverse reactions
  • Sponsors Sangamo Therapeutics
  • Most Recent Events

    • 07 Jun 2017 Biomarkers information updated
    • 06 Jan 2017 According to a Sangamo Therapeutics media release, this trial was originally conducted by Sangamo BioSciences but later on this company's name changed to Sangamo Therapeutics.
    • 06 Jan 2017 Planned primary completion date changed from 1 Mar 2018 to 1 Jun 2018.
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