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Neoadjuvant and Adjuvant Dabrafenib and Trametinib in Patients With Clinical Stage III Melanoma (Combi-Neo)

Trial Profile

Neoadjuvant and Adjuvant Dabrafenib and Trametinib in Patients With Clinical Stage III Melanoma (Combi-Neo)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 14 Feb 2024

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At a glance

  • Drugs Dabrafenib (Primary) ; Trametinib (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms Combi-Neo
  • Most Recent Events

    • 08 Feb 2024 Planned End Date changed from 1 Apr 2024 to 1 Apr 2025.
    • 08 Feb 2024 Planned primary completion date changed from 1 Apr 2024 to 1 Apr 2025.
    • 24 Oct 2023 Pooled analysis result of NCT02231775 and NCT02519322 trial assessing relapse free survival at 3 years by pathological response to neoadjuvant systemic treatment in patients with surgically resectable, high-risk melanoma (n=97) presented at the 48th European Society for Medical Oncology Congress.
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