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A Phase 1 Open-label, Dose Escalation Clinical Trial to Evaluate the Safety and Preliminary Biologic Activity/Efficacy of the VEGFR/PDGFR Inhibitor X-82 Administered Per Os in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Trial Profile

A Phase 1 Open-label, Dose Escalation Clinical Trial to Evaluate the Safety and Preliminary Biologic Activity/Efficacy of the VEGFR/PDGFR Inhibitor X-82 Administered Per Os in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Vorolanib (Primary) ; Ranibizumab
  • Indications Wet age-related macular degeneration
  • Focus Adverse reactions
  • Sponsors Tyrogenex; Xcovery Vision
  • Most Recent Events

    • 01 Jul 2017 Results published in the JAMA Ophthalmology
    • 08 Jun 2017 Results published in a Tyrogenex media release.
    • 08 Mar 2016 Status changed from active, no longer recruiting to completed as per ClinicalTrials.gov record.
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