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Phase I Study of Intramuscular (IM) Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia. PLX-PAD Are Mesenchymal-like Stromal Cells Derived From a Full Term Placenta. These Placental Adherent Stromal Cells (ASCs) Are Expanded in the Company's Proprietary PluriXTM 3D Bioreactor System. PLX Cells Are Immune Privileged and Possess Immunomodulatory Properties

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Trial Profile

Phase I Study of Intramuscular (IM) Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia. PLX-PAD Are Mesenchymal-like Stromal Cells Derived From a Full Term Placenta. These Placental Adherent Stromal Cells (ASCs) Are Expanded in the Company's Proprietary PluriXTM 3D Bioreactor System. PLX Cells Are Immune Privileged and Possess Immunomodulatory Properties

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Apr 2023

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At a glance

  • Drugs Emiplacel (Primary)
  • Indications Chronic limb-threatening ischemia
  • Focus Adverse reactions
  • Sponsors Pluri; Pluristem Therapeutics

    • Most Recent Events

    • 13 Mar 2023 rding to a Pluristem Therapeutics media release, Pluristem Therapeutics has changed its name to Pluri Inc.
    • 18 May 2015 According to a Pluristem Therapeutics media release, the PLX cell program in critical limb ischemia has been selected for the European Medicines Agency's Adaptive Pathways pilot project.
    • 27 Nov 2014 New trial record
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