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Phase 1b/2 Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Trial Profile

Phase 1b/2 Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 22 Apr 2024

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At a glance

  • Drugs Carfilzomib (Primary) ; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Hydrocortisone; Mercaptopurine; Methotrexate; Mitoxantrone; Pegaspargase; Vincristine
  • Indications Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Amgen; Onyx Pharmaceuticals
  • Most Recent Events

    • 15 Apr 2024 Planned End Date changed from 4 Aug 2024 to 14 Jul 2024.
    • 15 Apr 2024 Planned primary completion date changed from 14 May 2024 to 14 Jul 2024.
    • 15 Apr 2024 Status changed from recruiting to active, no longer recruiting.
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