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Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of ZGN-440 (Subcutaneous Beloranib in Suspension) in Obese Subjects With Type 2 Diabetes Mellitus to Evaluate Weight Reduction, Glycemic Control, Safety, and Tolerability

Trial Profile

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of ZGN-440 (Subcutaneous Beloranib in Suspension) in Obese Subjects With Type 2 Diabetes Mellitus to Evaluate Weight Reduction, Glycemic Control, Safety, and Tolerability

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Beloranib (Primary)
  • Indications Obesity
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Zafgen
  • Most Recent Events

    • 11 Jul 2018 Results evaluating efficacy and safety of Beloranib were published in the Diabetologia.
    • 11 Jun 2016 The FDA placed a full clinical hold on the beloranib IND in December 2015, according to a Zafgen media release.
    • 11 Jun 2016 According to a Zafgen media release, results from this trial were presented at the American Diabetes Association's 76th Scientific Sessions.
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