Study to Evaluate Cellular Adoptive Immunotherapy Using Polyclonal Autologous CD8+ Antigen-Specific T Cells for Metastatic Merkel Cell Carcinoma in Combination With MHC Class I Up-Regulation and the Anti-PD-L1 Antibody Avelumab

Trial Profile

Study to Evaluate Cellular Adoptive Immunotherapy Using Polyclonal Autologous CD8+ Antigen-Specific T Cells for Metastatic Merkel Cell Carcinoma in Combination With MHC Class I Up-Regulation and the Anti-PD-L1 Antibody Avelumab

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 Nov 2017

At a glance

  • Drugs Avelumab (Primary)
  • Indications Merkel cell carcinoma
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 09 Nov 2017 Status changed from suspended to recruiting.
    • 25 Sep 2017 Status changed from recruiting to suspended.
    • 06 Jun 2017 Results assessing the augmentation of adoptive T-cell therapy in patients from two related phase I/II trials (NCT01758458 and NCT02584829; n=8), presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
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