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Evaluating Efficacy When Transitioning From a Current Disease Modifying Therapy (DMT) to Ublituximab (ENHANCE)

Trial Profile

Evaluating Efficacy When Transitioning From a Current Disease Modifying Therapy (DMT) to Ublituximab (ENHANCE)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 18 Apr 2024

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At a glance

  • Drugs Ublituximab (Primary)
  • Indications Multiple sclerosis
  • Focus Registrational; Therapeutic Use
  • Acronyms ENHANCE
  • Sponsors TG Therapeutics Inc
  • Most Recent Events

    • 02 Mar 2024 Results (cohort 1 (n=13; 450 mg infusion, cohort 2 n=7; 450 mg infusion) assessing the tolerability of transition from anti-CD20 therapy to ublituximab, while eliminating the 150-mg starting dose, presented at the Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2024.
    • 01 Mar 2024 Interim Results published in the TG Therapeutics Media Release
    • 28 Feb 2024 According to TG Therapeutics, Inc media release, company presented first data from the ENHANCE Phase 3b trial evaluating patients who switch from another CD20 antibody to BRIUMVI.
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