A Phase 1b, Open-Label, Multi-Center, Dose Escalation Study of the Safety, Pharmacokinetics, and Therapeutic Activity of Cergutuzumab Amunaleukin, an Immunocytokine, Which Consists of a Variant of Interleukin 2 (IL 2v), That Targets Carcinoembryonic Antigen (CEA), and Atezolizumab, an Antibody That Targets Programmed Death-Ligand 1 (PD-L1), Administered Intravenously, in Patients With Locally Advanced and/or Metastatic Solid Tumors

Trial Profile

A Phase 1b, Open-Label, Multi-Center, Dose Escalation Study of the Safety, Pharmacokinetics, and Therapeutic Activity of Cergutuzumab Amunaleukin, an Immunocytokine, Which Consists of a Variant of Interleukin 2 (IL 2v), That Targets Carcinoembryonic Antigen (CEA), and Atezolizumab, an Antibody That Targets Programmed Death-Ligand 1 (PD-L1), Administered Intravenously, in Patients With Locally Advanced and/or Metastatic Solid Tumors

Recruiting
Phase of Trial: Phase I

Latest Information Update: 14 Sep 2017

At a glance

  • Drugs Cergutuzumab amunaleukin (Primary) ; Atezolizumab
  • Indications Solid tumours
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Sponsors Roche
  • Most Recent Events

    • 11 Sep 2017 Status changed from active, no longer recruiting to recruiting.
    • 31 May 2017 Planned End Date changed from 27 Jan 2018 to 26 Jan 2018.
    • 31 May 2017 Planned primary completion date changed from 27 Jan 2018 to 26 Jan 2018.
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