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Phase I dose escalation study of oral administration of S 78454 given as monotherapy in the treatment of patients with refractory or relapsed acute myeloid leukemia, acute lymphoblastic leukemia or high or intermediary-2 risk myelodysplastic syndrome

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Trial Profile

Phase I dose escalation study of oral administration of S 78454 given as monotherapy in the treatment of patients with refractory or relapsed acute myeloid leukemia, acute lymphoblastic leukemia or high or intermediary-2 risk myelodysplastic syndrome

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 29 Jan 2018

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At a glance

  • Drugs Abexinostat (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions
  • Sponsors Pharmacyclics; Servier

    • Most Recent Events

    • 29 Jan 2018 According to results published in the Leukemia and Lymphoma, the study was closed due to limited clinical benefit.
    • 29 Jan 2018 Status changed from active, no longer recruiting to discontinued, according to results published in the Leukemia and Lymphoma.
    • 17 Dec 2015 Status changed from active, no longer recruiting to completed as per ISRCTN: Current Controlled Trials.
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