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A Prospective, Open-label, Multicenter Phase-II Trial to Evaluate the Efficacy and Safety of a Sequential Regimen of Bendamustine Followed by GA101 and ABT-199 Followed by ABT-199 and GA101 Maintenance in CLL Patients

Trial Profile

A Prospective, Open-label, Multicenter Phase-II Trial to Evaluate the Efficacy and Safety of a Sequential Regimen of Bendamustine Followed by GA101 and ABT-199 Followed by ABT-199 and GA101 Maintenance in CLL Patients

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Sep 2022

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At a glance

  • Drugs Bendamustine (Primary) ; Obinutuzumab (Primary) ; Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Acronyms CLL2-BAG
  • Most Recent Events

    • 14 Sep 2022 Planned End Date changed from 1 Sep 2022 to 1 Nov 2024.
    • 17 Jun 2022 Results presented at the 27th Congress of the European Haematology Association
    • 14 Dec 2021 Results of polled analysis of pts aged 80 years or older in 6 phase II and III studies of the German CLL Study Group (GCLLSG) in the frontline-setting to elucidate outcomes of targeted treatments with regard to relevant clinical endpoints including overall survival and causes of death presented at the 63rd American Society of Hematology Annual Meeting and Exposition
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