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Long Term Clear Skin Maintenance Treatment Optimization in Patients With Moderate to Severe Chronic Plaque Psoriasis: A Randomized, Multicenter, Open-label With Blinded-assessment, Comparative, 52 Week Study to Evaluate the Efficacy, Safety and Tolerability of Secukinumab 300 mg s.c.

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Trial Profile

Long Term Clear Skin Maintenance Treatment Optimization in Patients With Moderate to Severe Chronic Plaque Psoriasis: A Randomized, Multicenter, Open-label With Blinded-assessment, Comparative, 52 Week Study to Evaluate the Efficacy, Safety and Tolerability of Secukinumab 300 mg s.c.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Secukinumab (Primary)
  • Indications Plaque psoriasis
  • Focus Therapeutic Use
  • Acronyms OPTIMISE
  • Sponsors Novartis; Novartis Pharma A.G.

    • Most Recent Events

    • 17 May 2019 Norway, Romania and Serbia were planned locations as per European Clinical Trials Database record.
    • 17 May 2019 Primary endpoint (Non-inferiority of q6w vs q4w dosing) has not been met as per results published in the British Journal of Dermatology.
    • 17 May 2019 Results published in the British Journal of Dermatology
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