An Investigator Sponsored Phase I/II Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia

Trial Profile

An Investigator Sponsored Phase I/II Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia

Suspended
Phase of Trial: Phase I/II

Latest Information Update: 20 May 2017

At a glance

  • Drugs Selinexor (Primary) ; Cladribine; Cytarabine; Plerixafor
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 10 Mar 2017 According to a Karyopharm Therapeutics media release, the FDA has placed selinexor (KPT-330) trials on partial clinical hold due to incomplete information in the existing version of the investigator's brochure (IB), Karyopharm has amended the IB and updated the informed consent documents accordingly and submitted to the FDA as requested.
    • 10 Mar 2017 Status changed from recruiting to suspended, according to a Karyopharm Therapeutics media release
    • 02 Jul 2015 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.
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