Trial Profile
An Open-label, Dose-ranging, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Lonafarnib With Ritonavir-Boosting +/- Peginterferon Alfa-2a in Patients Chronically Infected With Delta Hepatitis (HDV) (LOWR-2)
Status:
Completed
Phase of Trial:
Phase II
Latest Information Update: 23 Feb 2023
Price :
$35
*
At a glance
- Drugs Lonafarnib (Primary) ; Peginterferon alfa-2a (Primary) ; Ritonavir (Primary)
- Indications Hepatitis D
- Focus Adverse reactions; Proof of concept; Therapeutic Use
- Acronyms LOWR HDV-2; LOWR-2
- Sponsors Eiger BioPharmaceuticals
- 08 Nov 2022 Results of retrospective study (n=5; from Phase 2 LOWR 1 and LOWR 2 studies) assessing the effect of oral LNF based therapy of 3 to 12 months duration with long term follow up delineating durable off treatment biochemical and viral efficacy presented at The Liver Meeting 2022: 73rd Annual Meeting of the American Association for the Study of Liver Diseases
- 03 Dec 2021 Results published in the Hepatology
- 17 Apr 2018 Results published in the Media Release