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A Clinical Trial to Document Safety and Radiological Disease Activity in Patients With Relapsing-remitting Multiple Sclerosis Treated With Autologous CD4+ T Cells, Stimulated and Expanded ex Vivo by a Myelin Oligodendrocyte Glycoprotein Peptide Modified by the Introduction of a Thioreductase Motif Into the Flanking Residues of the Cell Epitope - A First-in-human Trial (SCLEROLYM TRIAL)

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Trial Profile

A Clinical Trial to Document Safety and Radiological Disease Activity in Patients With Relapsing-remitting Multiple Sclerosis Treated With Autologous CD4+ T Cells, Stimulated and Expanded ex Vivo by a Myelin Oligodendrocyte Glycoprotein Peptide Modified by the Introduction of a Thioreductase Motif Into the Flanking Residues of the Cell Epitope - A First-in-human Trial (SCLEROLYM TRIAL)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs MOG transduced T cells ImCyse (Primary)
  • Indications Multiple sclerosis
  • Focus Adverse reactions; First in man
  • Acronyms SCLEROLYM
  • Sponsors ImCyse

    • Most Recent Events

    • 04 Aug 2016 Status changed from completed to discontinued.
    • 16 Jul 2016 Status changed from recruiting to completed.
    • 23 Apr 2015 New trial record
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