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A Study of Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+Metastatic Breast Cancer Who Have Prior Received Anthracyclin, Taxane or Trastuzumab

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Trial Profile

A Study of Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+Metastatic Breast Cancer Who Have Prior Received Anthracyclin, Taxane or Trastuzumab

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 14 Jul 2022

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At a glance

  • Drugs Pyrotinib (Primary) ; Capecitabine; Lapatinib
  • Indications Advanced breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Jiangsu Hengrui Medicine Co.

    • Most Recent Events

    • 07 Jun 2022 Results of pooled analysis from (NCT01937689,NCT02361112,NCT02422199,NCT03080805) presented at the 58th Annual Meeting of the American Society of Clinical Oncology
    • 31 May 2020 Results (N=63), pooled analysis of three trials, assessing efficacy of pyrotinib plus capecitabine pts with HER2-positive, trastuzumab-resistant relapsed or metastatic breast cancer, presented at the 56th Annual Meeting of the American Society of Clinical Oncology
    • 31 May 2020 Results of pooled analysis investigating the efficacy of pyrotinib plus capecitabine as first-line treatment in patients with HER2-positive relapsed or metastatic breast cancer presented at the 56th Annual Meeting of the American Society of Clinical Oncology
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