A Phase II Clinical Trial of MK-3475 (Pembrolizumab) in Subjects With Relapsed or Refractory (R/R) Classical Hodgkin Lymphoma (cHL)

Trial Profile

A Phase II Clinical Trial of MK-3475 (Pembrolizumab) in Subjects With Relapsed or Refractory (R/R) Classical Hodgkin Lymphoma (cHL)

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Aug 2017

At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Hodgkin's disease
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms KEYNOTE-087
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 05 May 2017 According to a Merck AG media release, based on data from the KEYNOTE-087 and KEYNOTE-013 trials European Medicines Agency (EMA) has approved KEYTRUDA (pembrolizumab), for the treatment of adult patients with relapsed or refractory classical Hodgkin lymphoma (cHL) who have failed autologous stem cell transplant (ASCT) and brentuximab vedotin (BV), or who are transplant-ineligible and have failed BV.
    • 24 Mar 2017 The recommendation will be reviewed by the European Commission for marketing authorization in the European Union. A decision on approval is anticipated in the second quarter of 2017, as reported in a Merck & Co media release.
    • 24 Mar 2017 According to a Merck & Co media release, based on data from the KEYNOTE-087 and KEYNOTE-013 trials the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion recommending approval of KEYTRUDA, for the treatment of adult patients with relapsed or refractory classical Hodgkin lymphoma who have failed autologous stem cell transplant and brentuximab vedotin (BV), or who are transplant-ineligible and have failed BV.
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