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Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI Refractory Thyroid Cancers With the Combination of BRAF Inhibitor Vemurafenib and Anti-ErbB3 Antibody KTN3379: A Pilot Study With a Phase 1 Run-in

Trial Profile

Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI Refractory Thyroid Cancers With the Combination of BRAF Inhibitor Vemurafenib and Anti-ErbB3 Antibody KTN3379: A Pilot Study With a Phase 1 Run-in

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 May 2022

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At a glance

  • Drugs CDX-3379 (Primary) ; Vemurafenib (Primary)
  • Indications Carcinoma; Thyroid cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Celldex Therapeutics Inc; Kolltan Pharmaceuticals
  • Most Recent Events

    • 03 Apr 2017 Status changed from active, no longer recruiting to completed.
    • 27 Jun 2016 Status changed from recruiting to active, no longer recruiting.
    • 26 Feb 2016 Planned End Date changed from 1 Jul 2016 to 1 Mar 2017, as reported by ClinicalTrials.gov.
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