Phase 1/2 Clinical Study of Niraparib in Combination With Pembrolizumab in Patients With Advanced or Metastatic Triple-Negative Breast Cancer and in Patients With Recurrent Ovarian Cancer

Trial Profile

Phase 1/2 Clinical Study of Niraparib in Combination With Pembrolizumab in Patients With Advanced or Metastatic Triple-Negative Breast Cancer and in Patients With Recurrent Ovarian Cancer

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Aug 2017

At a glance

  • Drugs Niraparib (Primary) ; Pembrolizumab (Primary)
  • Indications Advanced breast cancer; Fallopian tube cancer; Male breast cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TOPACIO
  • Sponsors TESARO
  • Most Recent Events

    • 09 Aug 2017 According to a TESARO Inc. media release, data from this trial are expected to be presented at the European Society for Medical Oncology (ESMO) Congress 2017.
    • 03 Jun 2017 According to a TESARO media release, first expansion cohorts are now fully enrolled, and the second expansion cohorts for each tumor have been opened.
    • 03 Jun 2017 Results from dose escalation phase published in a TESARO Media Release.
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