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A Phase II, Dose Ranging, Multicenter, Double-blind, Placebo Controlled Study to Evaluate Safety and Effects of (R)-Roscovitine in Adults Subjects With Cystic Fibrosis, Carrying 2 Cystic Fibrosis Causing Mutations With at Least One F508del-CFTR Mutation and Chronically Infected With Pseudomonas Aeruginosa, a Study Involving 36 CF Patients (24 Treated, 12 Controls). ROSCO-CF

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Trial Profile

A Phase II, Dose Ranging, Multicenter, Double-blind, Placebo Controlled Study to Evaluate Safety and Effects of (R)-Roscovitine in Adults Subjects With Cystic Fibrosis, Carrying 2 Cystic Fibrosis Causing Mutations With at Least One F508del-CFTR Mutation and Chronically Infected With Pseudomonas Aeruginosa, a Study Involving 36 CF Patients (24 Treated, 12 Controls). ROSCO-CF

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Seliciclib (Primary)
  • Indications Cystic fibrosis
  • Focus Adverse reactions; Proof of concept
  • Acronyms ROSCO-CF

    • Most Recent Events

    • 01 Aug 2018 Status changed from recruiting to discontinued.
    • 17 Aug 2017 Planned End Date changed from 1 Oct 2017 to 1 Oct 2018.
    • 17 Aug 2017 Planned primary completion date changed from 1 Aug 2017 to 1 Aug 2018.
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