A Phase 1 Study to Investigate Absorption, Metabolism, and Excretion After Establishment of Steady State Via GBT440 Loading and Maintenance Dosing Followed by a Single Oral Dose Administration of [14C]-GBT440 in Healthy Male Subjects

Trial Profile

A Phase 1 Study to Investigate Absorption, Metabolism, and Excretion After Establishment of Steady State Via GBT440 Loading and Maintenance Dosing Followed by a Single Oral Dose Administration of [14C]-GBT440 in Healthy Male Subjects

Completed
Phase of Trial: Phase I

Latest Information Update: 17 Apr 2017

At a glance

  • Drugs GBT 440 (Primary)
  • Indications Sickle cell anaemia
  • Focus Pharmacokinetics
  • Sponsors Global Blood Therapeutics
  • Most Recent Events

    • 06 Dec 2016 Status changed from active, no longer recruiting to completed, according to results presented at the 58th Annual Meeting and Exposition of the American Society of Hematology.
    • 06 Dec 2016 Results assessing safety and pharmacokinetics presented at the 58th Annual Meeting and Exposition of the American Society of Hematology.
    • 04 Dec 2016 According to a Global Blood Therapeutics media release, data from this trial were presented at the 58th American Society of Hematology (ASH) Annual Meeting & Exposition
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