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A randomized, placebo controlled, double-blind, double-dummy, 3-period cross-over study in adult patients with autism spectrum disorders evaluating cognitive response, eye-gaze, and heart rate variability after single-dose oxytocin 8 or 24 IU intranasal administration using the OptiNose bi-directional nose-to-brain device.

Trial Profile

A randomized, placebo controlled, double-blind, double-dummy, 3-period cross-over study in adult patients with autism spectrum disorders evaluating cognitive response, eye-gaze, and heart rate variability after single-dose oxytocin 8 or 24 IU intranasal administration using the OptiNose bi-directional nose-to-brain device.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 Nov 2020

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At a glance

  • Drugs Oxytocin (Primary)
  • Indications Autistic disorder; Pervasive child development disorders
  • Focus Therapeutic Use
  • Sponsors OptiNose; OptiNose AS
  • Most Recent Events

    • 06 Nov 2020 Status changed from recruiting to completed.
    • 06 Oct 2015 Status changed from planning to recruiting, as per Optinose media release.
    • 21 Jul 2015 New trial record
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