Vaccines Against Salmonella Typhi: a phase IIb, single centre, observer-blind, randomised controlled trial to assess the immunogenicity and protective efficacy of Vi conjugated (Vi-TCV) and unconjugated (Vi-PS) polysaccharide vaccines in preventing typhoid infection compared to a control vaccine (meningococcal ACWY), using a human challenge model of typhoid infection

Trial Profile

Vaccines Against Salmonella Typhi: a phase IIb, single centre, observer-blind, randomised controlled trial to assess the immunogenicity and protective efficacy of Vi conjugated (Vi-TCV) and unconjugated (Vi-PS) polysaccharide vaccines in preventing typhoid infection compared to a control vaccine (meningococcal ACWY), using a human challenge model of typhoid infection

Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Jul 2015

At a glance

  • Drugs Typhoid vaccine Vi conjugate (Primary) ; Meningococcal vaccine groups A C Y W-135 conjugate; Typhoid vaccine Vi-polysaccharide
  • Indications Typhoid
  • Focus Therapeutic Use
  • Most Recent Events

    • 28 Jul 2015 New trial record
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