An Open-Label, Intrapatient, Dose-Escalation Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALXN1210 Administered Intravenously to Patients With Paroxysmal Nocturnal Hemoglobinuria.

Trial Profile

An Open-Label, Intrapatient, Dose-Escalation Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALXN1210 Administered Intravenously to Patients With Paroxysmal Nocturnal Hemoglobinuria.

Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Mar 2017

At a glance

  • Drugs Ravulizumab (Primary)
  • Indications Paroxysmal nocturnal haemoglobinuria
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Alexion Pharmaceuticals
  • Most Recent Events

    • 06 Dec 2016 Interim analysis results (n=13) presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
    • 04 Dec 2016 According to an Alexion Pharmaceuticals media release, interim data (n=13) from this trial presented at the 58th American Society of Hematology (ASH) annual meeting
    • 04 Dec 2016 Interim results (n=13) published in an Alexion Pharmaceuticals Media Release.
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