Trial Profile
An Open-Label, Intrapatient, Dose-Escalation Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALXN1210 Administered Intravenously to Patients With Paroxysmal Nocturnal Hemoglobinuria
Status:
Completed
Phase of Trial:
Phase I/II
Latest Information Update: 03 Nov 2023
Price :
$35
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At a glance
- Drugs Ravulizumab (Primary)
- Indications Paroxysmal nocturnal haemoglobinuria
- Focus Proof of concept; Therapeutic Use
- Sponsors Alexion AstraZeneca Rare Disease
- 17 Jun 2022 Results of pooled analysis assessing long-term complement inhibition and survival outcomes of ravulizumab in patients with paroxysmal nocturnal hemoglobinuria from phase 1b, 2 and 3 trials (103 [NCT02598583], 201 [NCT02605993], 301 [NCT02946463] and 302 [NCT03056040]) with up to 4 years of open-label extension, presented at the 27th Congress of the European Haematology Association.
- 22 Apr 2022 Status changed from active, no longer recruiting to completed.
- 21 May 2019 Planned End Date changed from 1 Aug 2018 to 1 Jun 2021.