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Efficacy and Safety of Pasireotide Long Acting Release (LAR) in Combination With Weekly Pegvisomant in Previously Controlled Acromegaly Patients on Combination Treatment of Long-Acting Somatostatin Analogues and Weekly Pegvisomant

Trial Profile

Efficacy and Safety of Pasireotide Long Acting Release (LAR) in Combination With Weekly Pegvisomant in Previously Controlled Acromegaly Patients on Combination Treatment of Long-Acting Somatostatin Analogues and Weekly Pegvisomant

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 26 Dec 2022

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At a glance

  • Drugs Pasireotide (Primary) ; Pegvisomant (Primary)
  • Indications Acromegaly
  • Focus Therapeutic Use
  • Acronyms PAPE
  • Most Recent Events

    • 27 May 2020 Results (n=45) assessing relationship between the predictors and the hormonal and tumoral responses to long-acting pasireotide (PAS-LAR) therapy compared with responsiveness to first-generation somatostatin receptor ligands, published in the European Journal of Endocrinology.
    • 18 Mar 2019 Results assessing T2-signal intensity and SST receptor expression in relation to the hormone and tumor response during PAS-LAR treatment presented at the 101st Annual Meeting of the Endocrine Society
    • 12 Oct 2018 Results (n=59) of the extension study of 48 weeks ,published in the European Journal of Endocrinology
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