A 12-week, Double-blind, Randomized, Placebo-controlled, Phase 2 Study, to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC) and an Inadequate Response to Ursodeoxycholic Acid (UDCA)

Trial Profile

A 12-week, Double-blind, Randomized, Placebo-controlled, Phase 2 Study, to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC) and an Inadequate Response to Ursodeoxycholic Acid (UDCA)

Discontinued
Phase of Trial: Phase II

Latest Information Update: 24 Oct 2017

At a glance

  • Drugs Seladelpar (Primary)
  • Indications Primary biliary cirrhosis
  • Focus Pharmacodynamics; Proof of concept
  • Sponsors CymaBay Therapeutics; Vitaflo
  • Most Recent Events

    • 24 Oct 2017 Results analysing the correlation between the pruritus visual analogue scale (VAS) and 5-D itch scale in primary biliary cholangitis (PBC) patients from NCT02609048 and NCT02955602 studies, presented at The Liver Meeting 2017: 68th Annual Meeting of the American Association for the Study of Liver Diseases
    • 15 Aug 2017 Results from this trial have been published in Lancet Gastroenterology and Hepatology, according to a CymaBay Therapeutics media release.
    • 13 Apr 2017 According to a CymaBay Therapeutics media release, data from this study will be presented at the International Liver Congress 2017 sponsored by the European Association for the Study of Liver Diseases (EASL).
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