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Phase 2, Randomized, Biomarker-driven Clinical Study in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With MCL-1 Dependence ≥30%

Trial Profile

Phase 2, Randomized, Biomarker-driven Clinical Study in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With MCL-1 Dependence ≥30%

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 18 Oct 2023

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At a glance

  • Drugs Alvocidib (Primary) ; Cytarabine; Mitoxantrone
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms Zella 201
  • Sponsors Sumitomo Pharma Oncology; Tolero Pharmaceuticals
  • Most Recent Events

    • 08 Dec 2020 Results (n=13) of newly diagnosed high-risk exploratory arm, presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology
    • 05 Dec 2020 Results presented in a Sumitomo Dainippon Pharma media release.
    • 05 Dec 2020 According Sumitomo Dainippon Pharma media release, data from this trial were presented at 62nd American Society of Hematology Annual Meeting
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