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A Randomized, Double-blind, Sponsor-open, Placebo-controlled, Single Intravenous Or Subcutaneous Dose Escalation Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Pf-06741086 In Healthy Subjects And An Open-label Evaluation In Healthy Japanese Subjects

Trial Profile

A Randomized, Double-blind, Sponsor-open, Placebo-controlled, Single Intravenous Or Subcutaneous Dose Escalation Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Pf-06741086 In Healthy Subjects And An Open-label Evaluation In Healthy Japanese Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Marstacimab (Primary) ; Marstacimab (Primary)
  • Indications Haemophilia
  • Focus Adverse reactions
  • Sponsors Pfizer
  • Most Recent Events

    • 08 Dec 2020 Results of post of analysis of data from NCT02974855 study and (biomarker data for healthy volunteers from phase 1 study NCT02531815 used as controls) assessing peak Thrombin and D-Dimer levels in subjects presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology
    • 16 Jun 2018 Results (n=41) published in the Journal of Thrombosis and Haemostasis.
    • 10 Aug 2016 Status changed from recruiting to completed.
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