A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Trial Profile

A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Sep 2017

At a glance

  • Drugs Tazemetostat (Primary)
  • Indications Rhabdoid tumour; Synovial sarcoma
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Epizyme
  • Most Recent Events

    • 02 Aug 2017 Planned End Date changed from 1 Jan 2018 to 1 Jan 2019.
    • 02 Aug 2017 Planned primary completion date changed from 1 Oct 2017 to 1 Jun 2018.
    • 01 Sep 2016 Planned number of patients changed from 84 to 108.
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