Evaluation of the Effect of 0.4 mg Nitroglycerin Spray After Pretreatment With Multiple Once Daily Oral Doses of 2.5 mg, 5 mg and 10 mg Vericiguat (BAY 1021189) Each Given Over 14 ± 3 Days on Safety, Tolerability and Blood Pressure in a Multi-center, Randomized, Placebo-controlled, Double-blind Group Comparison Study in Stable Coronary Artery Disease (CAD) Patients Aged 30 to 80 Years

Trial Profile

Evaluation of the Effect of 0.4 mg Nitroglycerin Spray After Pretreatment With Multiple Once Daily Oral Doses of 2.5 mg, 5 mg and 10 mg Vericiguat (BAY 1021189) Each Given Over 14 ± 3 Days on Safety, Tolerability and Blood Pressure in a Multi-center, Randomized, Placebo-controlled, Double-blind Group Comparison Study in Stable Coronary Artery Disease (CAD) Patients Aged 30 to 80 Years

Completed
Phase of Trial: Phase I

Latest Information Update: 15 Nov 2017

At a glance

  • Drugs Vericiguat (Primary) ; Nitroglycerin
  • Indications Angina pectoris; Coronary artery disease
  • Focus Adverse reactions
  • Acronyms VENICE
  • Sponsors Bayer
  • Most Recent Events

    • 15 Nov 2017 Results assessing safety presented at the 90th Annual Scientific Sessions of the American Heart Association.
    • 23 Aug 2016 Status changed from recruiting to completed.
    • 29 Apr 2016 Planned End Date changed from 1 Nov 2016 to 1 Jul 2016.
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