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An Open Label Phase Ib Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Maximum Tolerated Dose of Anetumab Ravtansine in Combination With Pemetrexed 500 mg/m2 and Cisplatin 75 mg/m2 in Subjects With Mesothelin-expressing Predominantly Epithelial Mesothelioma or Nonsquamous Non-small-cell Lung Cancer

Trial Profile

An Open Label Phase Ib Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Maximum Tolerated Dose of Anetumab Ravtansine in Combination With Pemetrexed 500 mg/m2 and Cisplatin 75 mg/m2 in Subjects With Mesothelin-expressing Predominantly Epithelial Mesothelioma or Nonsquamous Non-small-cell Lung Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Anetumab ravtansine (Primary) ; Cisplatin (Primary) ; Pemetrexed (Primary)
  • Indications Mesothelioma; Non-small cell lung cancer
  • Focus Adverse reactions
  • Sponsors Bayer
  • Most Recent Events

    • 06 Nov 2019 Status changed from active, no longer recruiting to completed.
    • 19 Sep 2019 Planned End Date changed from 28 Oct 2019 to 11 Nov 2019.
    • 19 Aug 2019 Planned End Date changed from 26 Sep 2019 to 28 Oct 2019.
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