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A Platform Study Exploring the Safety, Tolerability, Effect on the Tumor Microenvironment, and Efficacy of Pembrolizumab + INCB Combinations in Advanced Solid Tumors

Trial Profile

A Platform Study Exploring the Safety, Tolerability, Effect on the Tumor Microenvironment, and Efficacy of Pembrolizumab + INCB Combinations in Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Apr 2022

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At a glance

  • Drugs Itacitinib (Primary) ; Parsaclisib (Primary) ; Pembrolizumab
  • Indications Breast cancer; Colorectal cancer; Ductal carcinoma; Endometrial cancer; Gastric cancer; Head and neck cancer; Malignant melanoma; Non-small cell lung cancer; Pancreatic cancer; Renal cell carcinoma; Small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Adverse reactions
  • Sponsors Incyte Corporation
  • Most Recent Events

    • 30 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 02 Dec 2020 Planned End Date changed from 29 Sep 2020 to 24 Dec 2021.
    • 19 Dec 2019 Planned End Date changed from 1 Mar 2021 to 29 Sep 2020.
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