A Randomized Phase 3 Single Blind Study of Temozolomide Plus Radiation Therapy Combined With Nivolumab or Placebo in Newly Diagnosed Adult Subjects With MGMT-Methylated (Tumor O6-methylguanine DNA Methyltransferase) Glioblastoma

Trial Profile

A Randomized Phase 3 Single Blind Study of Temozolomide Plus Radiation Therapy Combined With Nivolumab or Placebo in Newly Diagnosed Adult Subjects With MGMT-Methylated (Tumor O6-methylguanine DNA Methyltransferase) Glioblastoma

Recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Nov 2017

At a glance

  • Drugs Nivolumab (Primary) ; Temozolomide
  • Indications Glioblastoma
  • Focus Registrational; Therapeutic Use
  • Acronyms CheckMate 548
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 03 Oct 2017 Planned primary completion date changed from 17 Jul 2019 to 29 May 2019.
    • 01 Sep 2017 Planned End Date changed from 8 Jan 2023 to 8 Jan 2022.
    • 01 Sep 2017 Planned primary completion date changed from 6 Nov 2021 to 17 Jul 2019.
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