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An Open-label, Nonrandomized, Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Belinostat in Patients With Relapsed/Refractory Solid Tumors or Hematological Malignancies Who Have Wild-Type, Heterozygous, and Homozygous UGT1A1*28 Genotypes

Trial Profile

An Open-label, Nonrandomized, Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Belinostat in Patients With Relapsed/Refractory Solid Tumors or Hematological Malignancies Who Have Wild-Type, Heterozygous, and Homozygous UGT1A1*28 Genotypes

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Oct 2022

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At a glance

  • Drugs Belinostat (Primary)
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Acrotech Biopharma
  • Most Recent Events

    • 10 Sep 2021 Status changed from recruiting to completed.
    • 04 Sep 2019 Planned End Date changed from 1 Jun 2019 to 1 Mar 2021.
    • 04 Sep 2019 Planned primary completion date changed from 1 Mar 2019 to 1 Mar 2021.
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