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A Phase 1 Study to Assess the Safety, Tolerability and Effectiveness of PV-10 Chemoablation of Neuroendocrine Tumours (NET) Metastatic to the Liver in the Reduction of Biochemical Markers and Symptoms Caused by Secretory Products

Trial Profile

A Phase 1 Study to Assess the Safety, Tolerability and Effectiveness of PV-10 Chemoablation of Neuroendocrine Tumours (NET) Metastatic to the Liver in the Reduction of Biochemical Markers and Symptoms Caused by Secretory Products

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Feb 2023

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At a glance

  • Drugs Rose bengal sodium (Primary)
  • Indications Colorectal cancer; Liver metastases; Neuroendocrine tumours; Pancreatic cancer
  • Focus Adverse reactions
  • Sponsors Provectus Biopharmaceuticals
  • Most Recent Events

    • 07 Feb 2023 Planned End Date changed from 1 May 2021 to 1 Sep 2023.
    • 21 Sep 2021 Results assessing intralesional (IL) PV-10, an autolytic immunotherapy that may elicit a disease-specific functional adaptive immune response in metastatic neuroendocrine neoplasms, presented at the 46th European Society for Medical Oncology Congress.
    • 08 Jun 2021 Results presented at the 57th Annual Meeting of the American Society of Clinical Oncology
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