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A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab 150 mg in Patients With Active nr- axSpA to Evaluate the Safety,Tolerability and Efficacy up to 2 Yrs, Followed by an Opt Phase of Either 150 mg or 300 mg Randomized Dose Escalation for up to Another 2 Yrs

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Trial Profile

A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab 150 mg in Patients With Active nr- axSpA to Evaluate the Safety,Tolerability and Efficacy up to 2 Yrs, Followed by an Opt Phase of Either 150 mg or 300 mg Randomized Dose Escalation for up to Another 2 Yrs

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 01 Jun 2023

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At a glance

  • Drugs Secukinumab (Primary)
  • Indications Axial spondyloarthritis; Non-radiographic axial spondyloarthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms PREVENT
  • Sponsors Novartis Pharma KK; Novartis Pharmaceuticals

    • Most Recent Events

    • 16 May 2023 Results assessing two year imaging outcomes from a phase 3 randomized trial of secukinumab in patients with non-radiographic axial spondyloarthritis. published in the Arthritis Research and Therapy
    • 04 Jun 2022 Results of post hoc analysis assessing efficacy outcomes of secukinumab in patients with non-radiographic axial spondyloarthritis presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 04 Jun 2022 Results of radiographic progression and the course of inflammation from PREVENT study presented at the 23rd Annual Congress of the European League Against Rheumatism
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