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A Randomized, Double-blind, Parallel Group Study to Evaluate the Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia Not Adequately Controlled With Their Statin Therapy

Trial Profile

A Randomized, Double-blind, Parallel Group Study to Evaluate the Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia Not Adequately Controlled With Their Statin Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Alirocumab (Primary) ; Atorvastatin; Ezetimibe; Rosuvastatin; Simvastatin
  • Indications Hypercholesterolaemia
  • Focus Therapeutic Use
  • Acronyms ODYSSEY EAST
  • Sponsors Sanofi
  • Most Recent Events

    • 18 Nov 2019 Primary endpoint (Percent Change From Baseline in Calculated Low Density Lipoprotein Cholesterol at Week 24: Intent-to-treat (ITT) Analysis) has been met, according to results presented at the American Heart Association Scientific Sessions 2019
    • 18 Nov 2019 Results assessing alirocumab efficacy and safety in patients with hypercholesterolemia at high cardiovascular risk were presented at the American Heart Association Scientific Sessions 2019
    • 13 Aug 2018 Status changed from active, no longer recruiting to completed.
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