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A Phase I/II Study of Combination Therapy of CG200745 PPA With Gemcitabine and Erlotinib to Determine the Maximum Tolerated Dose (MTD) and Evaluate the Safety and Efficacy for Locally Advanced Unresectable, or Metastatic Pancreatic Cancer

Trial Profile

A Phase I/II Study of Combination Therapy of CG200745 PPA With Gemcitabine and Erlotinib to Determine the Maximum Tolerated Dose (MTD) and Evaluate the Safety and Efficacy for Locally Advanced Unresectable, or Metastatic Pancreatic Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Sep 2022

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At a glance

  • Drugs Erlotinib (Primary) ; Gemcitabine (Primary) ; Ivaltinostat (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use
  • Sponsors CrystalGenomics
  • Most Recent Events

    • 14 Sep 2022 The maximum tolerated dose of ivaltinostat for the phase II trial was determined to be 250 mg/m2 as per results published in the International Journal of Cancer
    • 14 Sep 2022 Results published in the International Journal of Cancer
    • 13 Jun 2019 Status changed from recruiting to active, no longer recruiting.
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