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A Phase 1, Open-Label, Parallel-Group, Adaptive Study Evaluating the Pharmacokinetics of a Single Oral Dose of Momelotinib in Subjects with Hepatic Impairment (HI) and Healthy Matched Control Subjects with Normal Hepatic Function

Trial Profile

A Phase 1, Open-Label, Parallel-Group, Adaptive Study Evaluating the Pharmacokinetics of a Single Oral Dose of Momelotinib in Subjects with Hepatic Impairment (HI) and Healthy Matched Control Subjects with Normal Hepatic Function

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jan 2018

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At a glance

  • Drugs Momelotinib (Primary)
  • Indications Myelofibrosis
  • Focus Adverse reactions; Pharmacokinetics
  • Most Recent Events

    • 28 Dec 2017 Results of this and other study (renal impairment, profile:270241), published in the Journal of Clinical Pharmacology.
    • 20 Apr 2016 New trial record
    • 12 Mar 2016 Results presented at the 117th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
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