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An Open-Label, Multicenter, Dose-Escalation Phase Ib Study With Expansion Phase to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Therapeutic Activity of Emactuzumab and RO7009789 Administered in Combination in Patients With Advanced Solid Tumors

Trial Profile

An Open-Label, Multicenter, Dose-Escalation Phase Ib Study With Expansion Phase to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Therapeutic Activity of Emactuzumab and RO7009789 Administered in Combination in Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Emactuzumab (Primary) ; Selicrelumab (Primary)
  • Indications Advanced breast cancer; Colorectal cancer; Gastric cancer; Malignant melanoma; Mesothelioma; Ovarian cancer; Pancreatic cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions
  • Sponsors Roche
  • Most Recent Events

    • 01 May 2018 Status changed from active, no longer recruiting to completed.
    • 23 Apr 2018 Status changed from recruiting to active, no longer recruiting.
    • 29 Aug 2017 Planned End Date changed from 1 Jul 2018 to 28 Jul 2018.
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