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A Phase Ⅲ, Multi-center, Randomized, Controlled Study to Compare the Efficiency and Safety of SCT400(Recombinant Chimeric Anti-CD20 Monoclonal Antibody, Experimental Drug) Plus CHOP Versus Rituximab Plus CHOP in Untreated CD20-positive DLBCL Patients

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Trial Profile

A Phase Ⅲ, Multi-center, Randomized, Controlled Study to Compare the Efficiency and Safety of SCT400(Recombinant Chimeric Anti-CD20 Monoclonal Antibody, Experimental Drug) Plus CHOP Versus Rituximab Plus CHOP in Untreated CD20-positive DLBCL Patients

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 26 Dec 2022

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At a glance

  • Drugs Ripertamab (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Rituximab; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Sponsors Sinocelltech

    • Most Recent Events

    • 01 Dec 2022 Results assessing the efficacy, safety and immunogenicity of ripertamab and rituximab combined with CHOP as the first-line treatment for Chinese patients with CD20-positive diffuse large B cell lymphoma, published in the Hematological Oncology.
    • 14 Dec 2021 Primary endpoint (Overall response rate(ORR) after completion of treatment) has been met as per results presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 14 Dec 2021 Status changed from not yet recruiting to completed as per results presented at the 63rd American Society of Hematology Annual Meeting and Exposition
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