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Phase 1 Study of ACTR087, Autologous T Lymphocytes Expressing Antibody Coupled T-cell Receptors (CD16V-41BB-CD3ζ), in Combination With Rituximab, in Subjects With Relapsed or Refractory CD20-Positive B-Cell Lymphoma

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Trial Profile

Phase 1 Study of ACTR087, Autologous T Lymphocytes Expressing Antibody Coupled T-cell Receptors (CD16V-41BB-CD3ζ), in Combination With Rituximab, in Subjects With Relapsed or Refractory CD20-Positive B-Cell Lymphoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs ACTR 087/Rituximab combination therapy (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man
  • Acronyms ATTCK20-2
  • Sponsors Cogent Biosciences

    • Most Recent Events

    • 27 Mar 2020 Status changed from suspended to completed.
    • 12 Nov 2019 According to an Unum Therapeutics media release, data from this trial will be presented at the American Society of Hematology (ASH) Annual Meeting, December 7-10, Orlando, FL.
    • 06 Nov 2019 Results released in the 61st Annual Meeting and Exposition of the American Society of Hematology.
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