Trial Profile
A Randomized, Double-blind, Double-dummy, Parallel-group Study Comparing the Efficacy and Safety of Ofatumumab Versus Teriflunomide in Patients With Relapsing Multiple Sclerosis
Status:
Completed
Phase of Trial:
Phase III
Latest Information Update: 08 Apr 2024
Price :
$35
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At a glance
- Drugs Ofatumumab (Primary) ; Teriflunomide
- Indications Multiple sclerosis
- Focus Registrational; Therapeutic Use
- Acronyms ASCLEPIOS II
- Sponsors Novartis; Novartis Healthcare; Novartis Pharmaceuticals
- 02 Mar 2024 Results of subgroup analysis from the phase 3 ASCLEPIOS I/II trials assessing prognostic value of Serum Neurofilament Light Chain for future disease activity according to BMI and age in Patients With Relapsing Multiple Sclerosis presented at the Americas Committee for Treatment.
- 13 Oct 2023 Results assessing the effect of ofatumumab on serum IgG/IgM levels up to 5 years during the core and open-label extension studies (ASCLEPIOS I/II, APOLITOS, APLIOS & ALITHIOS) presented at the 9th Triennial joint meeting of Americas Committee for Treatment and Research in Multiple Sclerosis and the European Committee for Treatment and Research in Multiple Sclerosis.
- 13 Oct 2023 Results of pooled analysis (from studies ASCLEPIOS I/II for OFAand from FREEDOMS I, II and TRANSFORMS for FIN) assessing Indirect Treatment Comparison Methodologies to Differentiate the Efficacy of Ofatumumab and Other High Efficacy Therapies versus Orally Administered Disease Modifying Therapies for Relapsing Multiple Sclerosispresented at the 9th Triennial joint meeting of Americas Committee for Treatment and Research in Multiple Sclerosis and the European Committee for Treatment and Research